Figure 1. Experimental setup using the VIC-3D system

佩里博士开始使用完全笔直的硅胶管进行实验，该硅胶管是特别定制的，具有类似于血管的机械性能。他的实验装置如图1所示，在实验过程中支架将部署到硅胶管中并测量所产生的变形。Perry博士知道，企图对样品进行任何简化成点或线测量的方式都会对结果产生误导，而这正是VIC-3D系统的全场数据测量在实验过程的擅长所在，它让Perry博士对测量充满信心并提供了为客户发布准确结果所需的全部现场数据。

Dr. Perry began his experiments using perfectly straight silicone tubes that were custom made to have mechanical properties similar to a blood vessel. His experimental setup is shown above in Figure 1. The experiment involved deploying the stents into the tubes and measuring the resulting deformation. Dr. Perry knew that any simplified point or line measurement on his samples would have been misleading. This is where the VIC-3D system enters the experiment and provided Dr. Perry with the full field data he needed to be confident in his measurements and publish accurate results for his client.

Figure 2. Speckled silicone tube with stent inserted.

该实验所用硅胶管使用了现成的生物材料染色涂料来制作所需的散斑图案。以白色涂料覆盖了感兴趣的试验区域，然后使用黑色涂料来添加散斑点。上面的图2显示了已植入支架的具有散斑分布的硅胶管。

The silicone tube was prepared for the experiment by having a speckle pattern applied by using off the shelf spray paint. The area of interest was masked off and a white base coat applied. The black speckles were then simply added by using an over spray technique with black spray paint. Figure 2 above shows the speckled silicone tube with the stent inserted.

Figure 3. Change in radius contour under load from expanded stent.

对Dr. Perry最有价值的数据就是半径值的变化和由此产生的3D轮廓形貌，因为它清楚地表明最大的力位于支架末端附近。如上图3所示，该3D轮廓形貌图还指示了使用传统的测量技术可能未注意到的较大径向力分布区域。

The change in radius variable and resulting contour plot was the most valuable data for Dr. Perry because it clearly shows the largest force is located near the end of the stent. This contour plot, shown above in Figure 3, also indicates areas of larger radial force that could have gone unnoticed using traditional measurement techniques.

Figure 4. 3D change in radius contour plot showing displacement vectors.

Perry博士不仅获得了全场位移数据，而且还能够轻松地量化支架的径向力分布并显示由底层编织支架结构引起的周向变化。上面的图4以全场3D等高线图显示了支架的位移矢量信息，位移矢量显示了所产生的变形的大小，这使Perry博士可以轻松地解释数据并为其客户发布专业结果。VIC-3D系统使Perry博士对测量过程和结果充满信心。

Not only did Dr. Perry obtain full-field displacement data, he was also able to easily quantify the radial force profile of the stent and show the circumferential variation that resulted from the underlying woven stent structure.  Figure 4 above shows the displacement vectors of the stent in a full-field 3D contour plot. The displacement vectors show the magnitude of the resulting deformation which allows Dr. Perry to easily interpret the data as well as publish professional results for his client. The VIC-3D system gave Dr. Perry the ability to measure with confidence.

用户感言 Testimonial

“ Vic-3D是一个了不起的工具。 由于任何简化成直线或逐点的测量都将对分析结论产生误导，只有Vic-3D能够提供我们所需的可信任的全场数据测量结果。”

“Vic-3D was an amazing tool. Any simplified line or point-wise measurement would have been misleading. Vic-3D gave us full-field data we needed to be confident with the measurements.” -Dr. Kenneth Perry, ECHOBIO LLC

“我们需要强大的标定、数据文档和高保真度测量，因此我们采用VIC-3D系统并基于其相应地设计了我们的实验。”

“We needed robust calibration, documentation and high-fidelity measurements so we designed our experiment accordingly using the VIC-3D system.”

大鼠胫骨前肌运动的研究 Study Rat Tibialis Anterior Muscle Movements

技术挑战 Challenges

由于实验涉及活体组织，因此常规测量手段很难应用，并可能干扰研究中的运动。测量的关键点是如何尽可能快的获取尽可能多的数据。特定标记点的跟踪方法已有所使用，但仍只能提供总体平均值，而研究人员处理这类信息也费时费力。

Because the experiments involved live tissues, conventional gauges were difficult to apply and tended to interfere with the motion under study.  It was important to capture data quickly, and for as many points as possible.  Marker tracking had been used, but provided only gross averages.  It was also time-consuming and tedious for the researchers to process this type of  information.

 

 

解决方法 Solution

CSI公司的VIC-3D系统可快速捕捉整个肌肉表面的收缩数据。由于系统的速度和易用性，可以在精确的时间间隔内进行多次测量。该方法与被测标本没有相互作用的接触，全场数据也使得实验人员无须提前猜测哪些区域的测量更有意义。

Correlated Solutions’ VIC-3D system was used to rapidly capture contraction data over the entire muscle surface.  Due to the system’s speed and simplicity, it was possible to make numerous measurements at precisely timed intervals.  There was no interaction with the specimen, and no need to guess which areas would be of greatest interest.

测量结果提供了很高的空间分辨率，并且可以轻易的识别出许多由肌肉组织的“聚集”而引起显著收缩变化的区域，这些区域以前无法用传统的方法确定。最后，所有结果的计算都是自动完成。这节省了大量时间并避免了数据处理中出现人为错误的可能性。

The resulting measurements provided high spatial resolution and made it possible to identify numerous areas where “bunching” of the muscle tissue caused significant variations in muscle contraction.  These areas had not been previously identified with conventional methods.  Finally, all calculations were done automatically.  This saved considerable time and avoided the possibility of human error in the data processing.